Understanding Cortisol (AM & PM Levels): What They Mean for Your Health

Kamineni Diagnostic Centre, Dr.Kamineni Tulasi

What is Cortisol?

Cortisol is a hormone made by your adrenal glands. These small glands sit on top of your kidneys. Cortisol helps your body handle stress. It also controls blood sugar, blood pressure, and energy levels. Because of this, cortisol is sometimes called the “stress hormone.”

Why Do AM & PM Cortisol Levels Matter?

Cortisol (AM & PM levels) change during the day. In the morning, your body makes more cortisol to help you wake up. As the day goes on, levels drop. By evening, cortisol is much lower. This daily pattern is called a “diurnal rhythm.” Because of this, doctors often check both morning and evening cortisol levels. This helps them understand your body’s natural rhythm and spot any problems.

Normal Ranges for Cortisol (AM & PM)

Normal cortisol levels depend on the time of day. Usually, they are highest in the morning and lowest at night. Here are typical ranges (may vary by lab):

  • Morning (AM) cortisol: 6–23 micrograms per deciliter (mcg/dL)
  • Evening (PM) cortisol: 3–10 mcg/dL
  • However, normal cortisol levels can differ by age, health, and test method. Always check your lab’s reference range. If your results are outside these ranges, your doctor will help with cortisol test interpretation.

    Causes of Abnormal Cortisol Levels

    Sometimes, cortisol (AM & PM levels) are too high or too low. Many things can cause this, such as:

  • Chronic stress or anxiety
  • Adrenal gland problems (like Addison’s disease or Cushing’s syndrome)
  • Pituitary gland disorders
  • Use of steroid medicines
  • Sleep problems or shift work
  • Severe illness or infection
  • Because of these causes, it is important to look at both morning vs evening cortisol results.

    How is Cortisol Measured?

    Doctors use several ways to check your cortisol (AM & PM levels):

  • Blood test: A sample is taken, often in the morning and sometimes in the evening.
  • Saliva test: You spit into a tube, usually late at night, to check for low levels.
  • Urine test: You collect urine over 24 hours to measure total cortisol.
  • Each test helps your doctor see your daily pattern and spot any problems. For best results, follow your doctor’s instructions closely.

    Symptoms of High or Low Cortisol

    Abnormal cortisol (AM & PM levels) can affect your health in many ways. For example, high cortisol may cause:

  • Weight gain, especially around the belly
  • Thin skin or easy bruising
  • High blood pressure
  • Muscle weakness
  • Feeling anxious or moody
  • On the other hand, low cortisol may cause:

  • Fatigue or weakness
  • Weight loss
  • Low blood pressure
  • Nausea or vomiting
  • Dizziness, especially when standing
  • If you notice these symptoms, talk to your doctor. Early treatment can help prevent serious problems.

    Lifestyle Tips for Healthy Cortisol Balance

    Keeping your cortisol (AM & PM levels) in a healthy range is important. Here are some tips:

  • Get enough sleep each night
  • Eat balanced meals at regular times
  • Exercise regularly, but do not overdo it
  • Practice stress-reducing activities, like deep breathing or yoga
  • Limit caffeine and alcohol
  • Keep a regular daily routine
  • With these habits, you can support your body’s natural cortisol rhythm.

    Prevention and When to Seek Medical Advice

    Although you cannot always prevent cortisol problems, healthy habits can help. For example, managing stress and getting enough rest are key. If you have symptoms of high or low cortisol, or if your test results are abnormal, see your doctor. They can help with cortisol test interpretation and suggest the right treatment. Early care can protect your health and well-being.

    For personalized advice about your cortisol levels, consult a healthcare professional at Kamineni Diagnostic Centre. They can guide you based on your unique needs and health history.